Non-neurologic specific manifestations |
Fatigue, anorexia, dizziness, nausea, vomiting, weight loss, tachycardia |
Common neurological manifestations |
Learning and memory disturbance, confabulation |
Altered mental state: mental sluggishness, apathy, inattentiveness and inability to concentrate, spatial and personal disorientation, mild or marked confusion |
Ocular abnormalities: nystagmus, diplopia, upward gaze paresis, abducens palsy, conjugate gaze palsies |
Incoordination of gait and trunk ataxia |
Generalized hyporeflexia |
Disturbances of consciousness: drowsiness, lethargy, and mild coma |
Uncommon neurologic manifestations |
Stupor |
Dysarthria |
Hemiparesis, flaccid paraplegia, or quadriplegia |
Choreic dyskinesias |
Pupillary abnormalities: anisocoria, sluggish reactivity |
Optic neuropathy: amaurosis, visual disturbance, papilledema, retinal hemorrhage |
Epileptic seizures |
Hearing loss |
Hallucinations and behavioral disturbances |
Painful paresthesias: burning, prickling, or tingling |