Table 2.

Sensitivity and Specificity of Nucleic Acid Amplification Tests in Each Specimen Based on Nasopharyngeal Swab as a Reference.

	Sensitivity	Specificity
Saliva collected from patients without cough	0.90 (95% confidence interval (CI), 0.85-0.93)	0.98 (95% CI, 0.93-1.00)
Saliva collected from patients with cough	0.99 (95% CI, 0.94-1.00)	0.96 (95% CI, 0.83-0.99)
Oropharyngeal swab	0.76 (95% CI, 0.58-0.88)	0.98 (95% CI, 0.96-0.99)
Nasal vestibular swab	0.89 (95% CI, 0.83-0.94)	1.00 (95% CI, 0.99-1.00)
Middle turbinate swab	0.95 (95% CI, 0.83-0.99)	1.00 (95% CI, 0.89-1.00)
Nasal vestibular and oropharyngeal swab	0.95 (95% CI, 0.69-0.99)	0.99 (95% CI, 0.92-1.00)

Reproduced from Hanson KE, Caliendo AM, Arias CA, et al. The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: molecular diagnostic testing. Clin Infect Dis. 2021:ciab048 ⁽³⁾ with permission.