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. 2021 Apr 8;6(7):e134170. doi: 10.1172/jci.insight.134170

Figure 9. Illustration demonstrating mechanisms by which DLL4 haploinsufficiency programs altered lung vascular and alveolar development in mice.

Figure 9

AQP5, aquaporin 5; AT1, alveolar type I cell; DLL4, delta-like 4; Esr2, estrogen receptor 2; HOPX, homeodomain-only protein homeobox; JAG1, Jagged 1; Klf2, Kruppel-like factor 2; NICD, Notch intracytoplasmic domain; PDPN, podoplanin; VEGF, vascular endothelial growth factor.