Figure 7. Effect of ORMDL3 on ASM expression of mRNAs encoding calcium channels and calcium sensors.

(A) ASM cell surface Ca²⁺ channel expression including (A) Orai1 and (B) TRPC1 and TRPC3 mRNA were assessed by RT-qPCR in WT and hORMDL3^{Myh11eGFP-cre} ASM (n = 4–6/group). (C and D) ER-associated and calcium-sensing STIM1 and SARAF mRNA levels were also assessed via RT-qPCR in WT and hORMDL3^{Myh11eGFP-cre} ASM (n = 4–6/group). *P < 0.05 compared with WT. P values are results of unpaired 2-tailed t tests.