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(A) Growth rate in castrated NSG male mice (n = 5). (B) H&E histology (original magnification, ×200; inset [original magnification, ×400]). (C–H) IHC (original magnification, ×200) for (C) AR; (D) ERG (note positive staining in tumor endothelial cells); (E) HOXB13; (F) NFGR (pink) and p63 (brown) dual stain; (G) SYP; and (H) CHGA. NGFR, nerve growth factor receptor; SYP, synaptophysin; CHGA, chromogranin A.
