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(A and B) VEGFA165 induces pericytes to migrate. (C) The pericytes “sense” the VEGFA165 diffusing from vessels and align along the VEGFA165 gradient to form a “sprout.” The proliferation of ECs behind the tip cells drives the precapillary to elongate. (D) Newly proliferated pericytes on the new branch tube establish focal contacts with ECs.
