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. 2021 Mar 30;6(8):e141299. doi: 10.1172/jci.insight.141299

Figure 5. Ferritin is expressed in collecting duct cells and macrophages in patients with ADPKD.

Figure 5

(A) NHK and ADPKD sections were colabeled for ferritin (red) and DBA (a collecting duct marker, green). DAPI (a nuclear stain, blue) was used as a counterstain. Arrowheads show same cells with coexpression. Merged image from lower panels shows ferritin colocalization with DBA (arrowhead) in cyst-lining cells. Thin arrow shows interstitial cells with ferritin expression. Scale bar: 100 μm. (B) NHK and ADPKD sections were colabeled with ferritin (green) and CD68 (macrophage marker) (red). Arrowheads show coexpression of CD68 with ferritin. The area with arrowhead is amplified in the inset (bottom, right panel). Scale bar: 75 μm.