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. 2021 Apr 22;6(8):e145936. doi: 10.1172/jci.insight.145936

Figure 8. Plasma lipids of treated and untreated Sgpl1-KO mice.

Figure 8

Plasma (A) triglycerides, (B) total cholesterol, (C) HDL-cholesterol, and (D) non–HDL-cholesterol (LDL, IDL, and VLDL) were measured in plasma of WT (n = 8), heterozygous (HET) (n = 8), KO (n = 4), and AAV-SPL–treated KO (AAV) mice, (n = 5). All mice were euthanized at 28 DOL. For triglycerides, 1-way ANOVA was applied, and there were NSDs between any of the groups. For all other lipids, 1-way ANOVA was used to compare WT, HET, and AAV-SPL, and unpaired t test was used to compare KO and WT. Comparing KO vs. WT: (B, P = 0.0006); (C, P = 0.007); (D, P = 0.0002). There are NSDs between WT, HET, and AAV-SPL for any of the lipids.