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. 2021 Apr 8;6(7):e147610. doi: 10.1172/jci.insight.147610

Figure 1. Flow diagram showing patient selection and experiments.

Figure 1

Out of 85 enrolled patients with COVID-19 (67 hospitalized and 18 nonhospitalized), 6 hospitalized patients were excluded from analysis for absence of admission samples. Total ncfDNA and mtcfDNA were quantified from all study subjects via digital droplet PCR (ddPCR). A subset of hospitalized patients (n = 50: 30 ICU and 20 non-ICU) were subjected to whole genome bisulfite sequencing (WGBS). Among the 32 healthy controls enrolled, ddPCR and WGBS were performed in 31 and 19 healthy controls, respectively. All the patients with influenza or RSV were subjected to ddPCR and WGBS.