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. 2021 Apr 8;6(7):e147610. doi: 10.1172/jci.insight.147610

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© 2021 Andargie et al.

This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Receiver operating characteristic (ROC) curve analysis of cfDNA measures early at admission as predictor and maximum COVID-19 severity during illness as outcome variable. ROC analysis showing performance of cfDNA profiles to distinguish hospitalized patients who subsequently required ICU versus hospitalized patients who did not: (A) ncfDNA-, (B) monocyte-, (C) neutrophil-, (D) erythroblast-, (E) vascular endothelium– (F) adipocyte-, (G) hepatocyte-, (H) pancreas, (I) bladder-, (J) intestine-, (K) kidney-, (L) heart-, (M) lung-, and (N) head and neck larynx-derived cfDNA.