Table 1.
Demographics
| Healthy volunteers | First episode psychosis patients | |
|---|---|---|
| N | 20 | 20 |
| Age (years) mean (SD) | Mean = 27.15; SD = 6.12 |
Mean = 27.00 SD = 5.06 |
| Sex (male/female) | 20/0 | 20/0 |
| Ethnicity (CAUCASIAN/black African or Caribbean/Asian/mixed) | 7/2/9/2 | 10/4/5/1 |
| Diagnosis (schizophrenia/schizoaffective disorder) | N/A | 18/2 |
| Illness duration (months) mean (SD) | N/A |
Mean = 22.66; SD = 11.64 |
| Duration of prior treatment (if applicable) (months) mean (SD) | N/A |
Mean = 4.21 SD = 5.44 |
|
Current use of antipsychotics (yes/no) |
N/A | 0/20 |
| Prior use of antidepressant (yes/no) | N/A | 5/15 |
| Prior use of antipsychotics (yes/no) | N/A | 16/4 |
|
PANSS positive mean (SD) |
N/A |
Mean = 26.95 SD = 17.75 |
|
PANSS negative mean (SD) |
N/A |
Mean = 22.79 SD = 6.96 |
|
PANSS general mean (SD) |
N/A |
Mean = 39.74 SD = 10.77 |
|
PANSS total mean (SD) |
N/A |
Mean = 84.21 SD = 22.10 |
| PANSS five-factor positive mean (SD) | N/A | mean = 14.61 SD = 4.34 |
| PANSS five-factor negative mean (SD) | N/A | Mean = 24.94 SD = 7.28 |
| PANSS factor cognitive disorganization mean (SD) | N/A | Mean = 18.61 SD = 6.17 |
| PANSS five-factor depression/anxiety mean (SD) | N/A | Mean = 8.50 SD = 2.94 |
| PANSS five-factor excitability/hostility mean (SD) | N/A | Mean = 6.28 SD = 3.51 |
| Current cannabis use (yes/no) | 0/20 | 0/20 |
| Current alcohol use (yes/no/missing data) | 12/8/0 | 12/8/2 |
N sample size, FEP first episode psychosis, t independent samples t test, χ2 Chi-square, df degrees of freedom, N/A not applicable, SD standard deviation, BPRS brief psychiatric rating scale
All demographics reported in this table were reported previously [41]