Table 3.

Tissue gadolinium (Gd) concentrations 3 days following intra-articular injection

	μg Gd/g tissue, (median and range)
Group	Joint	Kidney	Bone marrow	Brain
Saline	< 0.1 (LOD)	< 0.1	< 0.1	< 0.1
High-dose gadodiamide	2.0 (0.7–4.6)	71 (65–89)	1.5 (0.2–2.1)	0.2 (0.1–0.2)
High-dose gadobutrol	0.5 (0.5–0.6)	14 (11–20)	0.1 (0.1–0.1)	< 0.1
Low-dose gadodiamide	0.2 (0.2–0.3)	1.2 (1.0–1.4)	0.1 (0.1–0.1)	< 0.1
Low-dose gadobutrol	< 0.1	0.2 (0.1–0.3)	< 0.1	< 0.1

LOD, assay limit of detection 0.1 μg Gd/g tissue