Table 3.

Alterations of ReHo among patients (at baseline, after 8 weeks of treatment) and controls

Cluster location	Peak coordinate			Cluster (voxel)	T value
	x	y	Z
Patients (both DPP and DT groups) at baseline versus controls
Left cerebellum VIII	− 27	− 57	− 51	36	3.3466
Right cerebellum X	21	− 45	− 42	23	3.3674
Left superior MPFC	− 21	51	− 15	31	− 4.174
Bilateral ventral MPFC	− 6	48	− 24	202	− 4.221
Right ITG	54	− 69	− 12	32	− 3.1499
Left superior TG	− 45	− 42	15	26	3.7986
Right triangular IFG	36	27	12	26	3.9728
Left triangular IFG	− 48	33	18	31	− 4.0695
Left superior FG	− 18	54	21	26	3.4123
Right Precuneus	9	− 54	42	23	− 3.5559
Left SMA	0	0	45	56	− 3.617
Left middle FG	− 27	6	60	23	− 3.4196
Right superior Parietal gyrus	33	− 57	60	30	4.2025
DPP group versus DT group at baseline
No cluster
DPP group after 8 weeks versus at baseline
Left superior MPFC	− 21	51	− 12	37	4.9128
Right precuneus	9	− 54	45	21	2.8237
Right Parahippocampal	30	− 21	− 27	21	3.7648
Left Rectus	0	48	− 24	20	2.9517
DT group after 8 weeks versus at baseline
Left ventral MPFC/ACC	− 6	39	− 12	79	6.0404
Left superior MPFC/ MFG	− 30	36	36	34	3.241
Left precuneus	− 9	− 72	39	29	3.5342
Left cerebellum VIII	− 27	− 60	− 54	22	− 3.7028
Right cerebellum VIII	21	− 51	− 33	31	− 3.8874
Right rectus	9	48	− 21	29	3.3901
Left IOG	− 30	− 75	− 6	23	− 3.2013
Left MFG	− 30	6	60	21	2.8294

The significance level was set at P < 0.05 corrected by the false discovery rate (FDR) method for multiple comparisons with the REST software (age and FD as covariates)

DPP drug plus psychotherapy, DT drug therapy, ReHo regional homogeneity, MPFC medial prefrontal cortex, IFG inferior frontal gyrus, ITG inferior temporal gyrus, SMA supplementary motor area, ACC anterior cingulate cortex, MFG middle frontal gyrus, IOG inferior occipital gyrus, FD framewise displacement