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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Bone Marrow Transplant. 2020 Dec 1;56(5):1090–1098. doi: 10.1038/s41409-020-01149-x

Table 2.

Cord blood-origin maternal microchimerism (CB-MMc) quantities according to time since CB transplantation (CBT): month-to-month fold-change estimated by the negative binomial model in the 7 patients with positive results are represented by the detection rate ratios (DRR) accompanied by their 95% confidence intervals (95%CI) and P-values. CB-MMc measurements were not independent and ‘clustered’ by CB unit (assuming each CB as an independent entity in the model). A month post-CBT was equivalent to the number of days post-CBT divided by 30.4375.

Month-to-month DRR [95%CI] of CB-MMc levels post-CBT P-value
Specimens
BMA 2.13 [1.78 – 2.55] < 0.0001
WB 0.88 [0.52 – 1.50] 0.651
 Neutrophils 1.41 [0.57 – 3.48] 0.454
 PBMC (unsorted) 1.20 [0.76 – 1.88] 0.431
  T cells 1.04 [0.63 – 1.71] 0.883
  B cells 0.35 [0.07 – 1.71] 0.195
  NK cells 2.9E+4 [2.3E−12 – 3.8E+20] 0.587
  Monocytes 2.16 [0.62 – 7.54] 0.228
Lineages
Myeloid (Neutro; Mono) 1.73 [0.81 – 3.66] 0.155
Lymphoid (T; B; NK) 1.31 [0.55 – 3.08] 0.542
Immune Function
Adaptive (T; B) 1.03 [0.48 – 2.20] 0.943
Innate (Neutro; Mono; NK) 1.71 [1.13 – 2.60] 0.011