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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Pain. 2021 Jun 1;162(6):1758–1770. doi: 10.1097/j.pain.0000000000002171

Figure 5. Behaviour responses of HomNav1.7I228M mutant mice to formalin and CFA injections.

Figure 5.

(A-B) Formalin test. HomNav1.7I228M mutant mice and their control littermates show similar licking durations in Phase I (WT, 165.6 ± 33.4 s, n=5; HomNav1.7I228M, 154.6 ± 15.8 s, n=5) and Phase II (WT, 246.4 ± 24.2 s, n=5; HomNav1.7I228M, 253.4 ± 32.2 s, n=5) of the formalin test. (C-D) Thermal and mechanical sensitivity measured by Hargreaves test and von Frey test following intra-plantar CFA injection. No significant difference is seen between WT (n=11) and HomNav1.7I228M (n=12) groups.