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. 2021 May 13;11:10173. doi: 10.1038/s41598-021-89700-8

Table 2.

Summary of mental health problems prevalence estimates among the general population, by WHO region and World Bank country groups.

Outcomes Overall WHO region World Bank groups
Africa region Region of the Americas South-East Asia Region European Region Eastern Mediterranean Region Western Pacific Region Lower-middle income Upper- middle income High income
Depression
No. of studies (participant) 75 (280,607) 2 (723) 10 (17,148) 8 (10,908) 19 (126,355) 5 (7236) 31 (118,237) 9 (8540) 34 (113,688) 32 (158,379)
Prevalence (95% CI) 28.0% (25.0–31.2) 20.6% (17.7–23.6) 34.2% (25.5–43.6) 41.0% (30.4–52.0) 26.4% (22.8–30.1) 32.1% (23.4–41.4) 24.1% (18.8–29.8) 39.3% (28.1–51.1) 26.0% (20.6–31.8) 27.3% (24.3–30.4)
I2 (95% CI) 99.7% (99.0–100) 99.1% (99.0–99.2) 99.2% (99.0–99.5) 99.5% (99.0–100) 98.4% (98.0–99.0) 99.8% (99.6–100) 99.1% (99.0–99.2) 99.7% (99.5–100) 99.4% (99.0–99.7)
P value for heterogeneity < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
P value for difference < 0.001 0.100
Anxiety
No. of studies (participant) 75 (284,813) 1 (502) 7 (4500) 9 (11,300) 18 (118,814) 8 (20,844) 32 (128,853) 11 (14,355) 34 (129,414) 30 (141,044)
Prevalence (95% CI) 26.9% (24.0–30.0) 49.6% (45.1–54.1) 40.0% (32.3–47.8) 32.9% (21.0–45.9) 26.2% (23.6–28.8) 30.6% (21.1–41.1) 21.7% (17.2–26.5) 32.6% (18.2–48.9) 26.0% (20.6–31.8) 26.0% (23.4–28.7)
I2 (95% CI) 99.7% (99.5–99.9) 96.3% (94.0–98.0) 99.4% (99.1–100) 98.8% (98.6–99.2) 99.5% (99.1–99.8) 99.7% (99.5–99.9) 99.7% (99.6–99.8) 99.8% (99.6–99.9) 99.1% (99.0–99.2)
P value for heterogeneity < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
P value for difference < 0.001 0.700
Post-traumatic stress symptoms
No. of studies (participant) 28 (56,447) 1 (502) 1 (898) 1 (653) 10 (34,322) 3 (1647) 12 (18,425) 4 (2268) 13 (19,342) 11 (34,837)
Prevalence (95% CI) 24.1% (17.0–32.0) 42.8% (38.4–47.3) 31.8% (28.8–35.0) 18.2% (15.3–21.4) 24.1% (15.8–33.5) 45.5% (33.0–58.3) 18.0% (5.9–34.8) 35.9% (21.9–51.3) 18.5% (6.8–34.3) 26.9% (18.6–36.2)
I2 (95% CI) 99.8% (99.7–100) 99.7% (99.5–99.9) 99.8% (99.5–99.9) 98.2% (97.1–99.3) 99.8% (99.6–100) 99.6% (99.5–99.7)
P value for heterogeneity < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
P value for difference < 0.001 0.260
Stress
No. of studies (participant) 22 (110,849) 1 (360) 6 (10,431) 6 (28,026) 9 (72,032) 5 (6427) 7 (64,164) 10 (40,258)
Prevalence (95% CI) 36.5% (30.0–43.3) 65.8% (60.7–70.7) 45.4% (30.0–61.3) 30.4% (22.5–39.0) 31.8% (23.7–40.3) 39.7% (24.4–56.1) 40.3% (19.5–63.0) 32.3% (26.2–38.7)
I2 (95% CI) 99.8% (99.7–100) 99.6% (99.4–99.8) 99.4% (99.2–99.7) 99.6% (99.5–99.7) 99.4% (99.2–99.7) 99.9% (99.7–100) 99.3% (99.1–99.4)
P value for heterogeneity < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
P value for difference < 0.001 0.580
Psychological distress
No. of studies (participant) 18 (81,815) 2 (1292) 1 (505) 7 (21,331) 3 (1913) 5 (56,774) 1 (505) 8 (58,437) 9 (22,873)
Prevalence (95% CI) 50.0% (41.8–58.2) 80.2% (78.0–82.3) 69.3% (65.1–73.3) 46.0% (33.0–59.2) 57.8% (16.3–93.5) 34.5% (21.9–48.4) 69.3% (65.1–73.3) 50.6% (33.6–67.6) 47.4% (35.4–59.4)
I2 (95% CI) 99.7% (99.5–100) 99.6% (99.5–99.7) 99.5% (99.2–99.7) 99.7% (99.5–99.9) 99.6% (99.5–99.7)
P value for heterogeneity < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
P value for difference < 0.001 < 0.001
Sleep problems (insomnia/poor sleep)
No. of studies (participant) 15 (99,534) 1 (502) 1 (4004) 3 (21,820) 10 (73,208) 1 (502) 11 (77,212) 3 (21,820)
Prevalence (95% CI) 27.6% (19.8–36.1) 15.1% (12.1–18.6) 53.9% (52.3–55.4) 30.0% (5.2–64.3) 25.6% (20.2–31.3) 15.1% (12.1–18.6) 28.1% (21.5–35.2) 30.0% (5.2–64.3)
I2 (95% CI) 99.8% (99.6–100) 99.2% (99.0–99.4) 99.6% (99.3–99.8)
P value for heterogeneity < 0.001
P value for difference < 0.001 < 0.001

CI confidence interval, WHO World Health Organisation.