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. 2021 May 13;11:10313. doi: 10.1038/s41598-021-89736-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Scheme illustrating the changes in nucleic acid composition in the evolution of insect postembryonic development. Amber represents the ancestral ametabolous mode, red the hemimetabolous mode characterized by nymphs with numerous instars, and blue the holometabolous mode characterized by larvae with fewer moult events before the pupa stage. No ametabolous species were analysed for nucleic acids in this study. The image is credit by I. Peralta-Maraver under CC BY open access copyright, and is based on Belles³.