Table 2.
Calculation of non-covalent interatomic interactions of wild-type and mutant CTC1 structures using the Arpeggio server.
| Variant | van der Waals interaction | Hydrogen bonds | Ionic interactions | Aromatic contacts | Hydrophobic contacts |
|---|---|---|---|---|---|
| WT | 97 | 117 | 18 | 29 | 387 |
| S730R | 101 | 115 | 20 | 31 | 399 |
| S730G | 98 | 117 | 18 | 31 | 388 |
| R731W | 106 | 119 | 16 | 51 | 409 |
| R744G | 95 | 116 | 15 | 31 | 382 |
| G767R | 105 | 117 | 18 | 33 | 390 |
| F800C | 100 | 118 | 18 | 20 | 339 |
| R806C | 97 | 117 | 18 | 31 | 386 |
| R806L | 98 | 117 | 18 | 31 | 386 |
| W807C | 97 | 117 | 18 | 25 | 366 |
| R818L | 102 | 114 | 14 | 31 | 393 |
| L860P | 102 | 118 | 18 | 31 | 375 |