Table 5.

Correlation by groups between biochemical markers, body composition and viral parameters with bone mineral density of the total hip in patients with chronic hepatitis B virus infection in use or not of antiretrovirals.

Variables	Total hip
	Group 1 Without antiretrovirals	p value	Group 1 Without antiretrovirals	p value	Group 1 Without antiretrovirals	p value
Age (years)	0.131	0.513	− 0.135	0.509	− 0.004	0.980
Viral load (log)	− 0.262	0.186	0.336	0.092	0.126	0.529
Medication time (years)	–	–	0.066	0.746	− 0.325	0.097
Vitamin D (ng/ml)	0.127	0.525	0.172	0.399	0.092	0.647
BMI (kg/m2)	0.482	0.010*	0.133	0.516	0.572	0.001*
Body fat (kg)	0.057	0.774	0.053	0.796	0.343	0.079
Lean Mass (kg)	− 0.014	0.943	− 0.043	0.833	− 0.136	0.497
IGF-1 (ng/ml)	0.005	0.978	0.049	0.811	− 0.012	0.949
DPD (nmol/mmol)	− 0.159	0.457	0.042	0.845	− 0.164	0.442
Osteocalcin (ng/ml)	− 0.135	0.528	− 0.263	0.212	− 0.571	0.003*
Total Calcium (mg/dl)	0.061	0.759	− 0.096	0.638	0.295	0.134
Phosphorus (mg/dl)	− 0.063	0.752	0.206	0.311	0.153	0.444
Magnesium (mg/dl)	− 0.233	0.241	0.029	0.887	0.392	0.043*
Urinary phosphorus (mg/l)	− 0.030	0.880	0.146	0.475	− 0.108	0.590
PTH (pg/ml)	− 0.019	0.922	− 0.339	0.089	− 0.296	0.132
FGF-23 (pg/ml)	− 0.027	0.918	− 0.406	0.105	0.347	0.171

Parameters with statistical differences are given in bold.

Pearson correlation, significance level p ≤ 0.05 indicated by *. DPD, deoxypyridinoline; PTH, parathormone; IGF-1, insulin-like growth factor-1; FGF-23, fibroblast growth factor 23; BMI, body mass index. FGF-23 n = 16–17 per group.