Fig. 1.

Derivation of triptan insufficient responder (TIR) and triptan sufficient responder (TSR) cohorts (N = 200), based on response to the question: “In approximately how many migraine attacks would you say your prescribed acute medication stops the pain entirely within 2 h of taking the medication?” TIRs were defined as patients who, after taking a triptan as an acute treatment, achieved headache pain freedom within 2 h in no more than three of five migraine attacks, whereas TSRs were defined as those who, after taking a triptan as an acute treatment, achieved headache pain freedom within 2 h in at least four of five migraine attacks