Table 1.
Summary of commercially available prognostic tests
Oncotype DX | MammaPrint | Prosigna | EndoPredict | Breast Cancer Index | CanAssist Breast | |
---|---|---|---|---|---|---|
No. of genes used | 21 | 70 | 50 | 8 | 7 | 5 biomarkers |
Proliferation genes included | Yes | Yes | Yes | Yes | No | No |
Method | qPCR | DNA microarray | NanoString | qPCR | qPCR | IHC |
Clinical parameters | No | No | No | Tumor size, node status | No | Tumor size, node status, and tumor grade |
Presence of intermediate zone | Yes | No | Yes | No | No | No |
Prediction of chemotherapy benefit | Yes | No | No | No | No | Yes |