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. 2021 Mar 15;10(1):287–314. doi: 10.1007/s40122-021-00244-1

Table 3.

Preventive drugs for migraine with strong evidence of efficacy

Drug class/drug name
Beta-blockers
Propranolol
Metoprolol
Atenolol
Anti-epileptics
Valproic acid
Topiramate
Antidepressants
Amitriptyline
Venlafaxine
Calcium antagonists
Flunarizine
CGRP-targeting monoclonal antibodies
Erenumab
Fremanezumab
Galcanezumab
Onabotulinum toxin A (for chronic migraine)

CGRP calcitonin gene-related peptide