Table 4.
Potential exams and tests for typical symptoms of fibromyalgia
| Symptom | Blood tests | Instrumental tools/clinimetrics for diagnosis |
|---|---|---|
| Intensity and type of pain | ESR | NRS |
| CRP | Semiotics of pain | |
| CPK | ||
| LDH | ||
| Stiffness | GAD antibodies | Zone mapping |
| Trigger point identification | ||
| Spasmophilia test | ||
| Hyperreflexia | Electrolytes | Spasmophilia test |
| Vitamin D | ||
| Small-fiber neuropathy | Skin biopsy | DN4 Questionnaire |
| Confocal optical microscopy | ||
| Metabolic alterations | Lactate-ammonia test | Lactate-ammonia test on cycloergometer |
| Trigger | Arthrosis | X-ray |
| Other conditions | MRI scan | |
| Ultrasound imaging | ||
| Muscular fatigue | CPK | Surface EMG |
| LDH | EMG | |
| TSH | ||
| Statin intake | ||
| Vitamin B12 | ||
| Folate | ||
| Selenium | ||
| Magnesium | ||
| Gastrointestinal alterations and intolerances (gluten, wheat, lactose) | Fecal calprotectin | Bioimpedance |
| Specific tests | Nutritional assessment |
CPK creatine phosphokinase, CRP C-reactive protein, DN4 Douleur Neuropathique 4, EMG electromyography, ESR erythrocyte sedimentation rate, GAD glutamic acid decarboxylase, LDH lactate dehydrogenase, MRI Magnetic Resonance Imaging, NRS Numerical Rating Scale, TSH thyroid-stimulating hormone