Table 2.
Expression of E-cadherin, VEGF, MMPs (MMP-1, MMP-2, MMP-9) in gastric cancer
| S. no. | Genes | Gastric cancer n (%) |
Normal control n (%) |
p value |
|---|---|---|---|---|
| 1. | VEGF | |||
|
Upregulated Downregulated No change |
7 (9.6%) 0 66 (90.4%) |
3 (11.1%) 0 24 (88.9%) |
> 0.05 | |
| 2. | E-cadherin | |||
|
Upregulated Downregulated No change |
10 (13.7%) 35 (47.9%) 28 (38.4%) |
4 (14.8%) 22 (81.5%) 1 (3.7%) |
< 0.01* | |
| 3. | MMP-1 | |||
|
Upregulated Downregulated No change |
10 (13.7%) 0 63 (86.3%) |
3 (11.1%) 0 24 (88.9%) |
> 0.05 | |
| 4. | MMP-2 | |||
|
Upregulated Downregulated No change |
21 (28.8%) 0 52 (71.2%) |
1 (3.7%) 0 26 (96.3%) |
< 0.01* | |
| 5. | MMP-9 | |||
|
Upregulated Downregulated No change |
8 (11%) 0 65 (89%) |
3 (11.1%) 0 24 (88.9%) |
> 0.05 | |