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. 2021 Apr 30;8:672028. doi: 10.3389/fmed.2021.672028

Figure 1.

Figure 1

Proposed clinical decision algorithm vaccination in sarcoidosis with or without prior COVID-19 infection. Recommendations are based on ACR guidance for COVID-19 vaccination in patients with rheumatic and musculoskeletal diseases (32) RTX, rituximab; TNF, tumor necrosis factor. *Current guidance recommends no adjustment in patients on anti-TNF alpha therapy. However, recent data suggests that in some patients on infliximab, the antibody response to SARS-CoV-2 may be blunted (33). At this time, it is unknown if this is applicable to sarcoidosis patients.