Table 4.
Predictive performance of fluid responsiveness for PPV, SVV, PPV/driving-P, and PPV/Crs among the three PEEP levels.
| PPV | SVV | PPV/driving-P | PPV/Crs | |
|---|---|---|---|---|
| PEEP 5 | ||||
| AUC | 0.81 (0.61–0.93) | 0.75 (0.55–0.90) | 0.75 (0.55–0.90) | 0.76 (0.55–0.90) |
| Cutoff | 3.2 | 4.5 | 0.26 | 0.1 |
| Sensitivity (%) | 100 (79.4–100) | 100 (79.4–100.0) | 87.5 (61.7–98.4) | 93.6 (69.8–99.8) |
| Specificity (%) | 54.6 (23.4–83.3) | 54.6 (23.4–83.3) | 63.6 (30.8–89.1) | 54.6 (23.4–83.3) |
| PEEP 10 | ||||
| AUC | 0.67 (0.46–0.84) | 0.79 (0.59–0.92) | 0.72 (0.52–0.88) | 0.67 (0.47–0.84) |
| Cutoff | 4.6 | 10.4 | 0.42 | 0.15 |
| Sensitivity (%) | 75 (47.6–92.7) | 50 (24.7–75.3) | 62.5 (35.4–84.8) | 68.8 (41.3–89.0) |
| Specificity (%) | 63.6 (30.8–89.1) | 100 (71.5–100) | 81.8 (48.2–97.7) | 63.6 (30.8–89.1) |
| PEEP 15 | ||||
| AUC | 0.85 (0.66–0.96) | 0.76 (0.55–0.90) | 0.88 (0.69–0.97) | 0.71 (0.50–0.86) |
| Cutoff | 8.8 | 11.5 | 0.48 | 0.32 |
| Sensitivity (%) | 75 (47.6–92.7) | 62.5 (35.4–84.8) | 81.3 (54.5–96.0) | 68.8 (41.3–89.0) |
| Specificity (%) | 90.9 (58.7–99.8) | 100 (71.5–100) | 90.9 (58.7–99.8) | 72.7 (39.0–94.0) |
AUC area under the receiver operating characteristic curve, PPV pulse pressure variation, SVV stroke volume variation, Crs respiratory system compliance.