Table 1.

Clinico-pathological characteristics of patient cohort in TMA analysis. Chi-squared test was used to assess statistical significance.

	Responders n = 71 (68.27%)		Non-responders n = 33 (31.73%)		Total n = 104
	n or median	% or IQR	n or median	% or IQR	n or median	% or IQR	p-value
Age	75	68–80	75	64–79	75	65–80	0.5255
Gender
Male	54	77.14	25	75.76	79	75.96	0.8767
Female	16	22.86	8	24.24	24	23.08
ECOG
0	32	45.71	15	45.45	47	45.2	0.3789
1	20	28.57	13	39.39	33	31.73
2	17	24.29	2	6.06	19	18.27
3	1	1.43	3	9.09	4	3.85
Tumor stage
T2	66	95.31	27	96.3	93	83.65	0.791
T3	5	3.13	6	3.7	11	2.88
CIS
No	37	52.11	17	51.52	54	51.92	0.8588
Yes	26	36.62	11	33.33	37	35.58
LVI
Absent	40	57.14	17	51.52	57	54.81	0.3386
Present	18	25.71	12	36.36	30	28.85