Table 3.

Association result for MetS model.

Set name	SNP	LKMRa p-value	Beta	SE	CIc (lower, upper)		OR b	Max (T)d p-value
S1	rs11216126	< 0.0001	− 0.062	0.05284	− 0.1659	0.04124	0.9	0.2382
	rs11556024		− 0.067	0.0846	− 0.2329	0.09873	0.9	0.4278
	rs11216129		− 0.057	0.05328	− 0.1616	0.04726	0.9	0.2833
	rs12292921		0.2862	0.07402	0.1411	0.4313	1.3	0.0001
	rs180326		0.1293	0.0387	0.05347	0.2052	1.1	0.0008
S2	rs2075295	0.938	− 0.003	0.0399	− 0.08132	0.07511	0.9	0.93
S3	rs17519079	< 0.0001	− 0.057	0.0894	− 0.2319	0.1185	0.9	0.52
	rs4938310		− 0.133	0.04784	− 0.2263	− 0.03876	0.8	0.005
	rs3741301		− 0.056	0.04173	− 0.1374	0.0262	0.9	0.18
	rs918144		0.0974	0.0381	0.0227	0.1721	1.1	0.01
	rs10488698		− 0.119	0.07948	− 0.2751	0.0365	0.8	0.13
	rs623908		− 0.042	0.03834	− 0.1176	0.03275	0.9	0.26
	rs17120029		0.245	0.07447	0.09909	0.391	1.2	0.0009
	rs1942478		− 0.105	0.05997	− 0.2225	0.01254	0.9	0.07
	rs2075294		− 0.098	0.08	− 0.255	0.05858	0.9	0.21
	rs2266788		0.2609	0.05131	0.1604	0.3615	1.3	3.663E − 07
	rs619054		− 0.097	0.04493	− 0.1854	− 0.009276	0.9	0.03
	rs651821		0.2773	0.05403	0.1714	0.3832	1.3	2.867E − 07

^aLogistic Kernel machine regression.

^bOdd ratio for minor allele.

^c95% Confidence interval for BETA.

^dMAX(T) p-value with 1,000,000 replications.