Table 1.
Descriptive results of potential risk factors and outcomes.
| Variables | Overall (n = 431) | XDR-AB Colonized (n = 77) | Not XDR-AB Colonized (n = 354) | P-value |
|---|---|---|---|---|
| Age (years), median (IQR) | 60.15 (49, 72) | 60.36 (50.5, 71.5) | 60.11 (49, 73) | 0.919 |
| Male, n (%) | 292 (67.7) | 56 (72.7) | 236 (66.7) | 0.302 |
| Season, n (%) | ||||
| Spring | 147 (34.1) | 24 (31.2) | 123 (34.7) | 0.907 |
| Summer | 103 (23.9) | 18 (23.4) | 85 (24.0) | 0.811 |
| Autumn | 75 (17.4) | 15 (19.5) | 60 (16.9) | 0.497 |
| Winter | 106 (24.6) | 20 (26.0) | 86 (24.3) | 0.599 |
| Charlson Index, mean ± SD | 4.22 ± 2.146 | 4.52 ± 2.180 | 4.16 ± 2.136 | 0.181 |
| Comorbidities, n (%) | ||||
| Cardiovascular diseases | 166 (38.5) | 41 (53.2) | 125 (35.3) | 0.003 |
| Chronic renal insufficiency | 61 (14.2) | 10 (13.0) | 51 (14.4) | 0.746 |
| COPD | 95 (22.0) | 24 (31.2) | 71 (20.1) | 0.033 |
| Type II diabetes mellitus | 101 (23.4) | 28 (36.4) | 73 (20.6) | 0.003 |
| Solid tumor | 106 (24.6) | 10 (13.0) | 96 (27.1) | 0.009 |
| Hematologic malignancy | 8 (1.9) | 2 (2.6) | 6 (1.7) | 0.595 |
| Current or former smoker | 160 (37.1) | 35 (45.5) | 125 (35.3) | 0.095 |
| Admission source, n (%) | ||||
| Emergency department | 110 (25.5) | 17 (22.1) | 93 (26.3) | 0.178 |
| Operation theater | 106 (24.6) | 18 (23.4) | 88 (24.9) | 0.936 |
| Normal wards | 126 (29.2) | 19 (24.7) | 107 (30.2) | 0.761 |
| Other hospital | 89 (20.6) | 23 (29.9) | 66 (18.6) | 0.072 |
| Primary reason for ICU admission, n (%) | ||||
| Neurological | 53 (12.3) | 5 (6.5) | 48 (13.6) | 0.087 |
| Suspected sepsis | 101 (23.4) | 28 (36.4) | 73 (20.6) | 0.003 |
| Respiratory | 129 (29.9) | 25 (32.5) | 104 (29.4) | 0.592 |
| Cardiovascular (excluding stroke) | 65 (15.1) | 11 (14.3) | 54 (15.3) | 0.830 |
| Multiple trauma | 25 (5.8) | 3 (3.9) | 22 (6.2) | 0.430 |
| Burns | 7 (1.6) | 3 (3.9) | 4 (1.1) | 0.082 |
| Hepatobiliary and pancreatic | 21 (4.9) | 0 (0.0) | 21 (5.9) | 0.028 |
| Gastrointestinal | 19 (4.4) | 1 (1.3) | 18 (5.1) | 0.142 |
| Genitourinary | 11 (2.6) | 1 (1.3) | 10 (2.8) | 0.442 |
| APACHE II score, mean ± SD | 15.278 ± 8.837 | 19.273 ± 8.871 | 15.409 ± 8.600 | <0.001 |
| Intensity of care, n (%) | ||||
| Renal replacement therapy | 71 (16.5) | 20 (26.0) | 51 (14.4) | 0.013 |
| Invasive ventilation for more than 5 days | 209 (48.5) | 64 (83.1) | 145 (41.0) | <0.001 |
| Vasopressor treatment for more than 3 days | 100 (23.2) | 28 (36.4) | 72 (20.3) | 0.003 |
| XDR-AB infection, n (%) | 30 (7.0) | 17 (22.1) | 13 (3.7) | <0.001 |
| Clinical outcomes | ||||
| Length of stay in ICU, median (IQR) | 18.85 (3, 83) | 28.58 (3,76) | 16.74 (3,83) | <0.001 |
| 28-day mortality, n (%) | 67 (15.5) | 12 (15.6) | 55 (15.5) | 0.992 |
| Six-month mortality, n (%) | 207 (48.0) | 53 (68.8) | 154 (43.5) | <0.001 |
Data are number (%), median (IQR), or mean ± SD. XDR-AB, extensively drug-resistant Acinetobacter baumannii; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; APACHE, Acute Physiology and Chronic Health Evaluation; IQR, interquartile range; SD, standard deviation.