Table 5.
Multivariate Cox regression model for Factors Associated with mortality in 6-month (XDR-AB colonization included).
| Variables | HR (95%CI) | P-value |
|---|---|---|
| XDR-AB colonization | 1.749 (1.174–2.608) | 0.006 |
| Age | 1.019 (1.007–1.032) | 0.002 |
| APACHE II Score | 1.127 (1.105–1.149) | <0.001 |
| Charlson Index | 0.978 (0.892–1.071) | 0.629 |
| Presence of cardiovascular diseases | 1.013 (0.712–1.442) | 0.942 |
| Presence of chronic renal insufficiency | 1.126 (0.755–1.677) | 0.561 |
| Presence of COPD | 1.545 (1.050–2.274) | 0.027 |
| Presence of type II diabetes mellitus | 0.845 (0.595–1.199) | 0.345 |
| Presence of solid tumor | 0.857 (0.545–1.347) | 0.503 |
| Presence of hematologic malignancy | 0.998 (0.365–2.728) | 0.997 |
| Neurological diseases as primary reason for ICU admission | 0.299 (0.046–1.934) | 0.205 |
| Suspected sepsis as primary reason for ICU admission | 0.258 (0.041–1.647) | 0.152 |
| Respiratory diseases as primary reason for ICU admission | 0.262 (0.041–1.668) | 0.156 |
| Cardiovascular (excluding stroke) diseases as primary reason for ICU admission | 3.855 (1.047–14.902) | 0.045 |
| Multiple trauma as primary reason for ICU admission | 0.262 (0.037–1.865) | 0.181 |
| Burns as primary reason for ICU admission | 0.217 (0.022–2.172) | 0.193 |
| Hepatobiliary and pancreatic diseases as primary reason for ICU admission | 0.058 (0.007–1.045) | 0.108 |
| Gastrointestinal diseases as primary reason for ICU admission | 0.179 (0.025–1.304) | 0.090 |
| Genitourinary diseases as primary reason for ICU admission | 0.286 (0.037–2.191) | 0.228 |
| Invasive ventilation for more than 5 days | 0.858 (0.624-1.178) | 0.343 |
| Renal replacement therapy | 0.962 (0.642-1.443) | 0.852 |
| Vasopressor treatment for more than 3 days | 8.295(5.710–12.051) | <0.001 |
XDR-AB colonization was treated as a time-dependent variable in the Cox regression model. HR, hazard ratio; APACHE, Acute Physiology and Chronic Health Evaluation; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; XDR-AB, extensively drug-resistant Acinetobacter baumannii.