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. 2021 Apr 30;12:633910. doi: 10.3389/fimmu.2021.633910

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Copyright © 2021 Baumgaertner, Sankar, Herrera, Benedetti, Barras, Thierry, Dangaj, Kandalaft, Coukos, Xenarios, Guex and Harari

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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tSNE of all clusters identified by MegaClust. (A) tSNE plot showing all clusters and populations identified by MegaClust. The different cell populations are color-coded and listed on the right. One group contains clusters of cells that where not assigned. (B) Cumulative analysis on all patients and timepoints (n=20) of the expression level (mean fluorescence intensity, MFI) of different markers on the 10 unassigned clusters. (C) tSNE plot showing all clusters and populations identified by MegaClust, with the 10 clusters identified by MegaClust that could not be assigned to known reference populations highlighted with distinct colours.