Table 3.

Multivariable Cox regression analysis of variables potentially associated with increased risk of tumor progression, de novo tumor development and survival time in 79 dogs with digital squamous cell carcinoma.

	Covariates	HR (95% CI)	P
Tumor progression	Duration of symptoms >90 daysa	1.7 (0.7–3.8)	0.216
	Multiple tumors at presentation	1.5 (0.4–5.4)	0.520
	Adjuvant medical treatment	2.9 (1.2–7.2)	0.018*
Development of new digital lesions	Multiple tumors at presentation	4 (1.2–13.2)	0.023*
	Adjuvant medical treatment	3.4 (1.2–9.4)	0.019*
Tumor-related death	Schnauzer breed	3.9 (1.7–9.2)	0.002*
	Metastasis at admission	5.8 (1.8–18)	0.002*
	Adjuvant medical treatment	2.8 (1.2–6.9)	0.021*

HR, hazard rato; CI, confidence interval.

^aMedian used as cut-off value.

^*Significant.