Fig. 3.

Pyroptosis‐related factors, inflammation‐related factors and miR‐223‐3p were abnormally expressed in monosodium urate (MSU)‐induced gout arthritis (GA) rats. (a–f) The expression levels of NLR family pyrin domain containing 3 (NLRP3), apoptosis‐associated speck‐like protein (ASC), cleaved caspase‐1, cleaved N‐terminal gasdermin D (GSDMD) and interleukin (IL)‐1β in the joint tissues of the rats were detected by Western blot; β‐actin was used as an internal control; (g) The expression of miR‐223‐3p in the serum of the rat joint tissues was detected by reverse transcription–quantitative polymerase chain reaction (RT–qPCR) (^*** P < 0·001 versus sham).