FIGURE 2.

Effect of BEO treatment on anxiety‐like behavior of rats induced by TiO2 NPs in the open field test. (a) the frequency of access to central area in the open field test. (b) the number of rearings in the open field test. (c) the total distance moved in open field test. (d) the distance moved within the center area. (e) the ratio of center distance to the total distance. Results were the mean ± SEM (N = 6). * p < .05; BEO, bergamot essential oil; TiO2 NPs, titanium dioxide nanoparticles; CTL, control; OFT, open field test