Table 3.
Baseline characteristics of the participants without any regular medication. Data are shown as median (interquartile range) for continuous variables and percentage (n) for discrete variables.
| All (3,307) | Men (2,122) | Women (1,185) | |
|---|---|---|---|
| Sex (Women) | 35.8% (1,185) | 0% (0) | 100.0% (1,185) |
| Age [y] | 48.0 (42.0/56.0) | 48.0 (42.0/56.0) | 48.0 (42.0/56.0) |
| BMI [kg/ m2] | 25.6 (23.3/28.4) | 26.2 (24.1/28.9) | 24.2 (22.0/27.1) |
| Obesity (yes) | 16.0% (529) | 18.2% (386) | 12.1% (143) |
| Diabetes (yes) | 1.2% (39) | 1.2% (26) | 1.1% (13) |
| Hypertension (yes) | 26.9% (889) | 31.5% (668) | 18.6% (221) |
| Dyslipidemia (yes) | 18.4% (605) | 25.5% (536) | 5.8% (69) |
| Kidney function | |||
| Creatinine [mg/dl] | 0.81 (0.73/0.90) | 0.87 (0.80/0.94) | 0.71 (0.66/0.76) |
| eGFR [ml/min/1.73 m2] | 99.7 (91.5/106.7) | 100.0 (92.3/107.2) | 98.8 (90.3/106.0) |
| Albuminuria | 3.5% (113) | 3.6% (75) | 3.3% (38) |
| Biomarkers | |||
| Cholesterol [mg/dl] | 217 (193/244) | 218 (194/244) | 216 (191/245) |
| Triglycerides [mg/dl] | 96 (72/135) | 107 (79/151) | 81 (63/106) |
| LDL-cholesterol [mg/dl] | 138 (118/162) | 142 (122/164) | 132 (111/157) |
| HDL-cholesterol [mg/dl] | 54.0 (45.6/65.6) | 50.0 (43.0/58.0) | 65.0 (55.0/75.0) |
| HbA1c [%] | 5.4 (5.1/5.6) | 5.4 (5.1/5.6) | 5.4 (5.1/5.6) |
| CRP [mg/l] | 1.2 (0.5/2.2) | 1.2 (0.5/2.2) | 1.2 (0.5/2.2) |
| Uric acid [mg/dl] | 4.7 (3.8/5.6) | 5.3 (4.6/6.0) | 3.5 (3.0/4.2) |
| Urea nitrogen [mg/dl] | 13.0 (11.0/16.0) | 14.0 (12.0/16.0) | 12.0 (10.0/14.0) |
| Albumin [g/l] | 42.0 (40.0/44.0) | 42.0 (40.0/44.0) | 42.0 (40.0/44.0) |
| ALAT [U/l] | 32 (25/42) | 36 (29/46) | 26 (21/32) |
| GGT [U/l] | 23 (16/35) | 28 (20/41) | 16 (13/22) |
| Alkaline phosphatase [U/l] | 63 (53/76) | 65 (55/76) | 62 (52/75) |
| Bilirubin [mg/dl] | 0.67 (0.52/0.89) | 0.72 (0.56/0.95) | 0.59 (0.45/0.78) |
| White cell count [1/nl] | 6.65 (5.58/7.90) | 6.54 (5.50/7.85) | 6.83 (5.73/8.00) |
| Red cell count [1/pl] | 4.79 (4.53/5.08) | 4.96 (4.73/5.18) | 4.51 (4.30/4.72) |
| Haemoglobin [g/dl] | 14.6 (13.8/15.4) | 15.1 (14.5/15.8) | 13.6 (13.0/14.2) |
| Homocystein [µmol/l] | 11.1 (9.4/13.3) | 11.8 (10.2/14.0) | 9.8 (8.3/11.6) |
| Cardiovascular function | |||
| Systolic glood pressure [mmHg] | 127 (117/137) | 130 (121/139) | 121 (111/132) |
| Diastolic blood pressure [mmHg] | 82 (76/89) | 84 (78/90) | 79 (73/85) |
| Ejection fraction [%] | 63.3 (60.0/66.7) | 62.9 (59.6/66.3) | 64.3 (60.8/67.2) |
| E/E'-Ratio | 6.45 (5.45/7.77) | 6.31 (5.32/7.62) | 6.71 (5.70/8.03) |
| Flow mediated dilatation [%] | 7.51 (4.66/11.09) | 6.32 (4.02/9.03) | 10.61 (6.78/14.49) |
| Augmentation index [%] | 8.52 (-2.18/22.52) | 3.91 (-5.44/15.78) | 17.56 (5.91/33.32) |