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. 2021 Apr 30;9:676588. doi: 10.3389/fcell.2021.676588

TABLE 2.

Brief reports of studies which assessed function of RMRP in cancer animal models (Δ: knock down or deletion).

Cancer types Animal models Function References
Hepatocellular carcinoma Male athymic Balb/c nude mice Δ RMRP: ↓ tumor size and weight Zhou et al. (2019)
Male Balb/c nude mice ↑ RMRP: ↓ tumor volume and weight Shao et al. (2020)
Cholangiocarcinoma Male nude mice Δ RMRP: ↓ tumor volume and weight Tang et al. (2019)
Gastric cancer Male BALB/c nude mice Δ RMRP: ↓ tumor growth Shao et al. (2016)
Neuroblastoma Female athymic nude mice Δ RMRP: ↓tumor volume and weight Pan et al. (2019)
Non-small cell lung cancer Male Balb/c nude mice Δ RMRP: ↓ tumor growth, migration and invasion Yang et al. (2020)
Multiple myeloma Male BALB/c-nude mice Δ RMRP: ↓ tumor growth Kong et al. (2019)