TABLE 3.
Outlines of studies reported expression of RMRP in cancerous clinical samples (OS: overall survival, ANTs: adjacent normal tissues).
| Cancer types | Samples | Expression (tumor vs. normal) | Kaplan-Meier analysis | References |
| Bladder cancer | 91 paired of BC tissues and adjacent tissues | Up | Lower RMRP expression correlated with better prognosis. | Cao et al. (2019) |
| Colorectal cancer (CRC) | 8 paired of CRC tissues and ANTs | Up | – | Park and Jeong (2015) |
| Hepatocellular carcinoma (HCC) | 52 paired of HCC tissues and ANTs | Up | Higher RMRP expression levels correlated with shorter OS in HCC patients compared with lower group. | Zhou et al. (2019) |
| 42 paired of HCC tissues and matched normal tissues | Up | RMRP high expression levels associated with decrease of OS rate in HCC patients. | Hongfeng et al. (2020) | |
| 40 paired of HCC tissues and ANTs | Down | High RMRP expression levels correlated with better 5-years and median survival rates in HCC patients. | Shao et al. (2020) | |
| Cholangiocarcinoma (CCA) | 33 paired of CCA tissues and ANTs | Up | Patients with lower RMRP expression levels had longer OS. | Tang et al. (2019) |
| Gastric cancer (GC) | 132 paired of GC and non-tumorous tissues | Up | – | Shao et al. (2016) |
| Glioma | 39 glioma tissues and 11 normal brain tissues | Up | Higher RMRP expression levels correlated with poorer OS in glioma patients than that of the lower group. | Feng et al. (2017) |
| Neuroblastoma | 44 paired of neonatal neuroblastoma tissues and ANTs | Up | Higher RMRP expression levels associated with poor prognosis in neonatal neuroblastoma patients. | Pan et al. (2019) |
| Non-small cell lung cancer (NSCLC) | Plasma specimens from 63 NSCLC patients and 33 cancer-free smoker individuals | Up | – | Lin et al. (2018) |
| 35 paired of lung adenocarcinoma tissues and ANTs | Up | – | Shao et al. (2016) | |
| 80 paired of NSCLC tissues and ANTs | Up | RMRP high expression levels associated with decrease of OS rate in NSCLC patients. | Yang et al. (2020) | |
| 38 paired of NSCLC tissues and ANTs | Up | Higher RMRP expression levels correlated with poorer OS in NSCLC patients compared to lower group. | Tang et al. (2019) | |
| Breast cancer (BC) | 8 paired of BC tissues and ANTs | Up | – | Park and Jeong (2015) |
| Papillary thyroid cancer (PTC) | 57 paired of PTC tissues and ANTs | Up | – | Wang et al. (2019) |
| Multiple myeloma (MM) | Bone marrow specimens from 28 MM patients and 10 healthy donors | Up | High RMRP expression levels correlated with shorter disease-free survival and OS in MM patients. | Kong et al. (2019) |