Table 1.
Demographic characteristics of N3-NSCLC patients.
| Characteristic | N = 24,747 (%) | |
|---|---|---|
| Age, years | Median (IQR) | 67 (59–75) |
| Race | White | 19,010 (76.8) |
| Black | 3,397 (13.7) | |
| Others | 2,340 (9.5) | |
| Sex | Male | 13,939 (56.3) |
| Female | 10,808 (43.7) | |
| Diagnosis year | 2010 | 3,847 (15.5) |
| 2011 | 3,865 (15.6) | |
| 2012 | 4,070 (16.4) | |
| 2013 | 4,158 (16.8) | |
| 2014 | 4,302 (17.4) | |
| 2015 | 4,505 (18.2) | |
| Laterality | Right | 13,145 (53.1) |
| Left | 10,224 (41.3) | |
| Unknown | 1,378 (5.6) | |
| Primary site | Upper lobe | 13,041 (52.7) |
| Middle lobe | 991 (4.0) | |
| Lower lobe | 5,854 (23.7) | |
| Main bronchus | 1,237 (5.0) | |
| Overlapping lesion | 253 (1.0) | |
| Unknown | 3,371 (13.6) | |
| Stage | IIIB | 6,762 (27.3) |
| IV | 17,985 (72.7) | |
| T stage | T1 | 2,767 (11.2) |
| T2 | 5,700 (23.0) | |
| T3 | 5,930 (24.0) | |
| T4 | 8,157 (33.0) | |
| TX | 2,193 (8.8) | |
| Bone metastasis | Yes | 7,093 (28.7) |
| No | 17,076 (69.0) | |
| Unknown | 578 (2.3) | |
| Brain metastasis | Yes | 4,571 (18.5) |
| No | 19,561 (79.0) | |
| Unknown | 615 (2.5) | |
| Liver metastasis | Yes | 3,163 (12.8) |
| No | 20,954 (84.7) | |
| Unknown | 630 (2.5) | |
| Lung metastasis | Yes | 6,886 (27.8) |
| No | 17,072 (69.0) | |
| Unknown | 789 (3.2) | |
| Histology | ADC | 13,674 (55.3) |
| SCC | 5,588 (22.6) | |
| Other NSCLC | 5,485 (22.1) | |
| Grade | I | 419 (1.7) |
| II | 2,468 (10.0) | |
| III | 6,389 (25.8) | |
| IV | 347 (1.4) | |
| Unknown | 15,124 (61.1) | |
| Surgery | Yes | 505 (2.0) |
| No | 24,242 (98.0) | |
| Chemotherapy | Yes | 16,865 (68.1) |
| No/unknown | 7,882 (31.9) | |
| Radiotherapy | Yes | 12,771 (51.6) |
| No/unknown | 11,976 (48.4) | |
| Radiation sequence | After surgery | 189 (0.8) |
| Before surgery | 46 (0.2) | |
| Others/unknown | 270 (1.1) | |
| No surgery | 24,242 (98.0) | |
| Distant metastasis | Bone | 2,400 (9.7) |
| Brain | 1,599 (6.5) | |
| Liver | 521 (2.1) | |
| Lung | 2,856 (11.5) | |
| ≥two sites | 5,882 (23.8) | |
| None | 10,457 (42.3) | |
| Unknown | 1,032 (4.2) | |
| Systematic therapy | Chemotherapy | 7,129 (28.8) |
| Radiotherapy | 3,035 (12.3) | |
| Both | 9,736 (39.3) | |
| None | 4,847 (19.6) | |
NSCLC, non-small cell lung cancer; IQR, interquartile range; ADC, adenocarcinoma; SCC, squamous cell carcinoma.