Table 2.

Association between neutrophil-to-lymphocyte ratio (NLR) and demographic and clinicopathologic parameters in 93 dogs with chronic enteropathy.

Parameter correlated with NLR	Spearman ρ	p value	pcorr value
Patient characteristics
Age	0.40	<0.0001	<0.0003
Body weight	−0.01	0.9432	NS
Clinical disease severity (CCECAI score)	0.41	0.0008	0.0024
Clinicopathologic variables
Biomarkers of gastrointestinal tract function
Serum cobalamin concentration	−0.18	0.109	NS
Serum folate concentration	−0.11	0.327	NS
Biomarkers of systemic inflammation or pancreatic disease
Serum CRP concentration	0.26	0.0478	0.0956
Serum calprotectin concentration	0.30	0.120	NS
Serum S100A12 concentration	0.29	0.0323	0.0969
Serum sRAGE concentration	−0.43	0.0344	0.138
Serum Spec cPL concentration	0.52	<0.0001	<0.0005
Biomarkers of gastrointestinal inflammation
Fecal calprotectin concentration	0.26	0.139	NS
Fecal S100A12 concentration	0.24	0.119	NS
Biomarkers of gastrointestinal protein loss
Serum albumin concentration	−0.36	0.0005	0.0010
Fecal α1PI concentration	0.47	0.0003	0.0009
Serum α1PI concentration	−0.10	0.451	NS
Serum-to-fecal α1PI ratio	−0.48	0.0003	0.0012

α₁PI = alpha₁-proteinase inhibitor; CCECAI = canine chronic enteropathy clinical activity index²; CRP = C-reactive protein; Spec cPL = specific canine pancreatic lipase; NS = not significant; p_corr = Holm–Bonferroni corrected p value (n = 2, 3, or 4); sRAGE = soluble receptor of advanced glycation end products.