Figure 5.

Identification of gene signatures associated with disease-free interval based on Cox-PH regression model. (A) Lasso coefficient profiles of the 495 progression- associated events in PCa. (B) Selection of the tuning parameter (λ) in the LASSO model through 10-fold cross-validation procedure was plotted as a function of log(λ). (C-D) Construction of multivariate Cox-PH regression model and ZNF695, CENPA, TROAP, BIRC5, KIF20A were considered significant and used to construct a prognostic model.