Table 2.
Multivariable analysis for 5-DFS and the C-index for single predictors.
| Parameters | Multivariable analysis | C-index (95% CI) | ||
|---|---|---|---|---|
| HR | 95%CI | P valuea | ||
| T stage (cm) | 0.625 (0.576-0.675) | |||
| T1 (T≤2) | 1.000 | |||
| T2 (2<T≤5) | 2.576 | 0.925-7.171 | 0.070 | |
| T3 (T>5) | 3.506 | 1.199-10.251 | 0.022 | |
| N status | 0.678 (0.635-0.721) | |||
| Negative | 1.000 | |||
| Positive | 3.854 | 2.201-6.747 | < 0.001 | |
| Histological grade | 0.684 (0.639-0.729) | |||
| I | 1.000 | |||
| II | 1.479 | 0.513-4.262 | 0.469 | |
| III | 4.250 | 1.413-12.782 | 0.010 | |
| ER status | 0.611 (0.563-0.659) | |||
| Negative | 1.000 | |||
| Positive | 0.568 | 0.325-0.995 | 0.048 | |
| PR status | ||||
| Negative | 1.000 | |||
| Positive | 1.076 | 0.640-1.807 | 0.783 | |
| HER2 gene | 0.588 (0.541-0.635) | |||
| Non-amplification | 1.000 | |||
| Amplification | 2.045 | 1.258-3.325 | 0.004 | |
| TSR | 0.555 (0.505-0.605) | |||
| Stroma-high | 1.000 | |||
| Stroma-low | 0.643 | 0.399-1.035 | 0.069 | |
T: tumor; N: node; TSR: tumor-stromal ratio; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor-2.