Table 2.
Relationship between the SIS and clinicopathological variables of patients
| Clinicopathological features | SIS | P value | ||
|---|---|---|---|---|
| 0 | 1 | 2 | ||
| Age (y) | 0.474 | |||
| <45 | 35 (39.8%) | 49 (43.8%) | 22 (34.4%) | |
| ≥45 | 53 (60.2%) | 63 (56.2%) | 42 (65.6%) | |
| FIGO stage | 0.020 | |||
| IB1 | 67 (76.1%) | 76 (67.8%) | 34 (53.1%) | |
| IB2 | 8 (9.1%) | 15 (13.4%) | 14 (21.9%) | |
| IIa | 13 (14.8%) | 21 (18.8%) | 16 (25.0%) | |
| Surgery | 0.191 | |||
| Open | 55 (62.5%) | 50 (44.6%) | 29 (45.3%) | |
| Lap | 33 (37.5%) | 62 (55.4%) | 35 (54.7%) | |
| Histological type | 0.493 | |||
| SCC | 70 (79.5%) | 82 (73.2%) | 51 (79.7%) | |
| AC | 15 (17.1%) | 23 (20.5%) | 8 (12.5%) | |
| Others | 3 (3.4%) | 7 (6.3%) | 5 (7.8%) | |
| Lymphovascular invation | <0.001 | |||
| No | 75 (85.2%) | 73 (65.2%) | 34 (53.1%) | |
| Yes | 13 (14.8%) | 39 (34.8%) | 30 (46.9%) | |
| Depth of invasion | <0.001 | |||
| <1/2 | 62 (70.5%) | 54 (48.2%) | 24 (37.5%) | |
| ≥1/2 | 26 (29.5%) | 58 (51.8%) | 40 (62.5%) | |
| Lymph node metastasis | <0.001 | |||
| No | 86 (97.7%) | 94 (83.9%) | 48 (75.0%) | |
| Yes | 2 (2.3%) | 18 (16.1%) | 16 (25.0%) | |
| NLR | 0.002 | |||
| <1.8 | 56 (63.6%) | 52 (46.4%) | 23 (35.9%) | |
| ≥1.8 | 32 (36.4%) | 60 (53.6%) | 41 (64.1%) | |
| PLR | 0.009 | |||
| <132.8 | 56 (63.6%) | 55 (49.1%) | 25 (39.1%) | |
| ≥132.8 | 32 (36.4%) | 57 (50.9%) | 39 (0.9%) | |
Abbreviations: SIS, Systemic Inflammatory Score; SCC, squamous cell carcinoma; AC, adenocarcinoma; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.