Table 3.
Multivariate analysis of clinicopathologic variables in relation to OS in patients
| Clinicopathological features | No. of patients | OS | |
|---|---|---|---|
| HR (95%CI) | P value | ||
| FIGO stage | 0.027 | ||
| IB1 | 177 | Reference | |
| IB2 | 37 | 1.285 (0.375-4.403) | |
| IIa | 50 | 4.053 (1.335-12.310) | |
| Lymphovascular invation | 0.033 | ||
| No | 182 | Reference | |
| Yes | 82 | 3.092 (1.093-8.741) | |
| Depth of invasion | 0.906 | ||
| <1/2 | 140 | Reference | |
| ≥1/2 | 124 | 0.933 (0.295-2.956) | |
| Lymph node metastasis | 0.025 | ||
| No | 228 | Reference | |
| Yes | 36 | 2.116 (1.014-5.746) | |
| NLR | 0.352 | ||
| <1.8 | 131 | Reference | |
| ≥1.8 | 133 | 1.632 (0.582-4.578) | |
| PLR | 0.162 | ||
| <132.8 | 136 | Reference | |
| ≥132.8 | 128 | 2.062 (0.747-5.90) | |
| SIS | 0.008 | ||
| 0 | 88 | Reference | |
| 1 | 112 | 3.639 (0.421-31.433) | |
| 2 | 64 | 11.733 (1.410-97.616) | |
Abbreviations: OS, overall survival; SIS, Systemic Inflammatory Score; NLR, neutrophil-to- lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.