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. 2021 Apr 30;12(12):3648–3659. doi: 10.7150/jca.52851

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NRP1 upregulated in GC tissue and linked with AJCC stage. (A) The GEPIA results revealed that NRP1 expression was significantly upregulated in the GC tissues. (B) The level of NRP1 was linked with the pathological stage of the tumor. The level of NRP1 in patients with stage III and IV was significantly higher than that of patients with stage I and II. (C) The representative image of NRP1 expression in GC tissues was detected by IHC. Scale bars were indicated. (D) The IHC staining score of NRP1 protein in GC tissues and paired normal mucosal tissues. GC, gastric cancer; NRP1, Neuropilin-1; IHC, Immunohistochemistry; *, P< 0.05; **, P< 0.01; ***, P< 0.001; ns, no significant.