Table 1.
Correlation between tumor NRP1 expression and clinicopathologic features of the gastric cancer cases
Factors | n | NRP1 expression | P value | |
---|---|---|---|---|
High (%) | Low (%) | |||
Age, years | 0.2424 | |||
<60 | 137 | 74 | 63 | |
≥60 | 73 | 46 | 27 | |
Gender | 0.4768 | |||
Male | 126 | 69 | 57 | |
Female | 84 | 51 | 33 | |
Tumor size (cm) | < 0.0001 | |||
≤5 | 114 | 34 | 80 | |
>5 | 96 | 86 | 10 | |
Tumor location | 0.8839 | |||
Distal | 104 | 58 | 46 | |
Body | 56 | 32 | 24 | |
Proximal | 50 | 30 | 20 | |
Differentiation | 0.3174 | |||
High | 8 | 3 | 5 | |
Moderate | 40 | 19 | 21 | |
Poor | 116 | 70 | 46 | |
Other | 46 | 28 | 18 | |
AJCC TNM stage | < 0.0001 | |||
I | 44 | 6 | 38 | |
II | 43 | 16 | 27 | |
III | 96 | 74 | 22 | |
IV | 27 | 24 | 3 | |
Depth of invasion | < 0.0001 | |||
T1 | 40 | 2 | 38 | |
T2 | 18 | 5 | 13 | |
T3 | 42 | 23 | 19 | |
T4 | 110 | 90 | 20 | |
Lymph node metastasis | < 0.0001 | |||
N0 | 58 | 13 | 45 | |
N1 | 43 | 17 | 26 | |
N2 | 38 | 25 | 13 | |
N3 | 71 | 65 | 6 | |
Distant metastasis | < 0.0001 | |||
Absent (M0) | 183 | 95 | 88 | |
Present (M1) | 27 | 25 | 2 | |
CEA (preoperative) (ng/ml) | 0.2925 | |||
≤5 | 71 | 37 | 34 | |
>5 | 139 | 83 | 56 |