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. 2021 Apr 15;11(13):6240–6250. doi: 10.7150/thno.55953

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3T D₂O MRI guidance for interventionally hyperosmotic BBBO in a dog. A) T_2w image pre-injection. B) D₂O MRI contrast-enhancement map. C) SPIO MRI contrast-enhancement map. D) Gd-contrast-enhancement map after the administration of mannitol. E) Correlation between SPIO- and D₂O- MRI. The Spearman coefficient (r) = 05350. F) Correlation between Gd- and D₂O- MRI. The Spearman coefficient (r) = 0.6009.