Figure 1.

DHA alleviates DSS induced colitis. (A) The survival rate of DSS-induced lethal colitis treated with PBS or DHA. A log-rank test was used to verify the Kapla-Meier curves. N = 8 in each group, p < 0.001. (B) Flowchart for establishing the early stage (the stage of chronic colitis) of CAC models. (C) Weight changes were monitored during the process of AOM/DSS murine model. (D) Disease activity index was measured for each treatment group. (E) The macroscopic appearance of the colon. (F) The colon length was measured. (G) Representative H&E staining for colon mucosa from each treatment group. N = 5 in control and DHA groups. N = 10 in AOM+DSS and AOM+DSS+DHA groups. Data are presented as mean ± SD. ** p < 0.01, **** p < 0.0001. ns: non-significantly.