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. 2021 Apr 15;11(13):6293–6314. doi: 10.7150/thno.57177

Figure 6.

Figure 6

Waterfall plot demonstrating PSA response of patients treated with varying doses of [177Lu]Lu-J591. Gray: 20-35 mCi/m2 × 2, Blue: 40 mCi/m2 × 2, Red: 45 mCi/m2 × 2. As the doses increased, the PSA response decreased. Adapted with permission from Nanus et al. Phase 1/2 study fractionated dose lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 (177Lu-J591) for metastatic castration-resistant prostate cancer. Cancer. 2019, 125 (15), 2561-2569.