Table 1.

Various nanoformulations for co-delivery of dual anticancer therapeutics

Nanoformulation	Combined therapeutics	Drug-loading mechanism	Target	Refs.
Polymeric micelle	THZ/DOX	Hydrophobic forces	Breast cancer	34
	DOX/PTX	Electrostatic forces/hydrophobic forces	Lung cancer	35
	PTX/TR3 siRNA	Hydrophobic forces/electrostatic forces	Pancreatic cancer	36
	Msurvivin T34A gene/DOX	Electrostatic forces/hydrophobic forces	Melanoma	37
Polymeric nanoparticle	Retinoic acid/DOX	Hydrophobic forces	Breast cancer	38
	AntimiR10b/antimiR-21	Electrostatic forces	Breast cancer	39
	CDDP/RAPA	Hydrophobic forces	Melanoma	29
	MiR-34a/DOX	Electrostatic forces/hydrophobic forces	Breast cancer	40
Liposome	RanGTP/DOX	Passive diffusion	Breast cancer	41
	PTX/TRAIL	Hydrophobic forces/electrostatic absorption	Melanoma	42
	VEGF siRNA/PTX	Electrostatic absorption/hydrophobic forces	Breast cancer	43
	DFO/YC-1	Passive diffusion/hydrophobic forces	Pancreatic cancer	44
MSN	CPT/DOX	Hydrophobic forces/covalent binding	Cervical cancer	45
	P-gp siRNA/DOX	Electrostatic absorption/hydrophobic forces	Breast cancer	46
Fe3O4 nanoparticle	DOX/CDDP	Covalent binding	Breast cancer	47
Nanogel	CDDP/DOX	Chelation/electrostatic interaction/π-π stacking interaction	Breast cancer	48
	Epigallocatechin gallate/siRNA	Electrostatic interaction	Breast cancer	32
NGO	ADM/anti-miR-21	Hydrophobic forces/electrostatic forces	Breast cancer	49