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. 2021 Apr 30;11:672047. doi: 10.3389/fonc.2021.672047

Table 1.

Longitudinal measurements of functional MRI parameters and tumor volume in Group A.

Group A base 3 days 6 days 9 days 12 days 15 days F P
D* (10-2mm2/s) 0.526 ± 0.027 0.449 ± 0.022 0.401 ± 0.026 0.374 ± 0.023 0.329 ± 0.025 0.311 ± 0.030 57.248 0.001
f (%) 22.2 ± 1.7 20.4 ± 2.0 19.2 ± 1.9 17.3 ± 1.5 16.3 ± 1.7 13.7 ± 1.9 17.319 0.001
D (10-3mm2/s) 0.395 ± 0.032 0.481 ± 0.033 0.556 ± 0.033 0.585 ± 0.030 0.619 ± 0.029 0.647 ± 0.035 51.177 0.001
ADC (10-3mm2/s) 0.432 ± 0.029 0.540 ± 0.050 0.602 ± 0.038 0.642 ± 0.039 0.690 ± 0.044 0.677 ± 0.038 35.341 0.001
R2* (s-1) 24.093 ± 0.736 23.563 ± 0.741 23.237 ± 0.765 23.354 ± 0.699 23.561 ± 0.720 22.819 ± 0.798 1.932 0.118
Tumor volume (mm3) 228.7 ± 49.2 323.5 ± 50.8 389.8 ± 52.4 457.1 ± 58.0 475.4 ± 54.9 529.8 ± 56.6 25.373 0.001

The F and P values represent the analysis results of one-way ANOVA.